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SIGNIFOR® (pasireotide) Injection is indicated for the treatment of adult patients with Cushing’s disease for whom pituitary surgery is not an option or has not been curative.
Highlights of Important Safety Information
- Treatment with SIGNIFOR may lead to decreases in circulating levels of cortisol resulting in biochemical and/or clinical hypocortisolism. SIGNIFOR dose reduction or interruption and/or adding low-dose short-term glucocorticoid therapy may be necessary.