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SIGNIFOR® (pasireotide) Injection is indicated for the treatment of adult patients with Cushings disease for whom pituitary surgery is not an option or has not been curative.

Highlights of Important Safety Information

  • Treatment with SIGNIFOR may lead to decreases in circulating levels of cortisol resulting in biochemical and/or clinical hypocortisolism. SIGNIFOR dose reduction or interruption and/or adding low-dose short-term glucocorticoid therapy may be necessary.
Highlights of the Prescribing Information full Prescribing Information